Start off with sketch (only picture i had of it) the left picture
Sketch Border lines - Notice i am using paper with a faint template on it - Made my own and printed it.
And ink in panel lines (if you have speech bubbles that overlap draw these as well - i forgot and had to crop them
Following your sketch again draw the characters and story and whatever (blue pencil means you dont have to erase it for scanning!)
And ink your sketch. I used a random Staedtler Fineliner - Use whatever you have
Rinse and Repeat
Scan, colour or tone, add text and print out (or publish digitally)
To make a booklet like in the photo, you can do this yourself using the booklet printing option in word, or make a pdf and use adobe, both work fine (You may have to experiment with putting the paper back in the printer to print the other side if you dont have double sided printing). You can then staple the pages using a staple gun and fold the staples back, or if you are lucky to have a long arm stapler, just use that :P A normal stapler will work, but you may have to crease the pages to get it to reach.
If you are very lucky, you will have a photocopier/printer with the whole feature and just bung the pages in, press go, and manga falls out the other end. I used the one i had at work (I actually have permission to use anything for my own personal projects), so i didn't have to fiddle with my own stapling, but i have used that technique before anyway so it still works.
I ended up giving copies of my manga to everyone in my department, two of which have sons who are into manga who said it was good :P
My whole setup: took 40 hours to make the whole thing from beginning to end